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How can nanotechnology using our skin and body sweat as a diagnostic tool to detect the presence of diseases.

Laboratory Analysis

Exploring the possibility of employing nanotechnology and using our skin and body sweat as a diagnostic tool to detect the presence of diseases.  The early days when our family physicians used to feel our skin to detect any abnormalities. Today, we have variable technology such as Skin Patches, which can provide for targeted drug delivery. This has been made possible due to evolution in the field of nanotechnology,  microelectronics, and biocompatible polymers. By using these technologies. We have already developed what is known as e-skin or electronic skin, which can provide for targeted drug delivery. The same technology can be used our sweat to treat. There is our body sweat as a diagnostic tool to detect diseases, sweat basically acts as a thermal regulator, and it regulates the inner temperature of our bodies. 99% of the sweat is comprised of water, and the remaining 1% is made up of different types of salts, such as sodium, chloride, potassium, calcium, magnesium, etc. The studies have shown that the concentration of salts in our sweat varies depending on our body temperature, which in turn undergoes a change if we are suffering from any diseases.
Our sweat glands are regulated by a few neurons, and the functioning of these neurons can be affected if we are suffering from diseases. So when a person is suffering from a disease changes will occur in the functioning of our neurons, and in the functioning of our sweat glands. And this, in turn, causes a change in the concentration of salts present in our bodies. This change in the concentration level of salts in our sweat can be detected through sweat analysis by making use of electronic skin. So in short, if e-skin is applied to carry out sweat analysis, then it can become a diagnostic tool to detect the presence of diseases. For example,  in a person suffering from cystic fibrosis, the ratio of sodium to chloride ions sweat is different from that of a normal person. Similarly, in the case of a person suffering from diabetes, there is a higher concentration of glucose found in the sweat. So by detecting these changes through sweat analysis,  we can diagnose diseases more efficiently.  Few studies show that specific sensory probes can be developed to detect the presence of specific salts. So if these salts specific sensory probes are attached to the skin, then it can provide for accurate sweat analysis, which can become an effective diagnostic tool. Then the data collected by the sensory probes can be transferred via Bluetooth technology to phones and other digital devices. Advances that we have already made in the field of nanotechnology and microelectronics can make this possible. Currently, such electronics skin patches are powered by micro-batteries, in the future, these skin patches can be powered by our sweat itself. Because the composition of our sweat is such that it can be easily engineered to become a power source for such e- Skin Patches. Human sweat is not known to carry any pathogen, such as a virus or bacteria. Because the sweat has a germ-killing protein, known as dermcidin.


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